An experimental gene-editing therapy that aims to lower bad cholesterol for the long-term after a single infusion is off to a positive start in an early clinical trial.

Researchers running a Phase I safety trial for the drug, dubbed VERVE-102, published interim results from just 35 patients this week in the New England Journal of Medicine . Though the numbers are small and the analysis is preliminary, VERVE-102 appeared safe, with no serious adverse events reported from the treatment, even at the largest doses. The most significant finding was a temporary, mild increase of a liver enzyme that suggested minor injury in the liver, where the drug works.

The small amount of data also hints that the drug is effective. The subgroup of participants who received the largest dose have seen their bad cholesterol—that is, their low-density lipoprotein or LDL—drop 62 percent, to a mean of 78 mg per deciliter. For people with high cholesterol—like the participants in the trial—a reduction of this magnitude could cut the risk of cardiovascular disease from plaque buildup in arteries by an estimated 50 percent if it's sustained for over 20 years. The trial only has up to 18 months of follow-up data so far, but from that, the positive effects of VERVE-102 seem to be holding up. The LDL reductions have been sustained in all the subgroups.

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Forecasters are calling for below-average activity this hurricane season, which begins Monday, June 1.

The National Weather Service is predicting eight to 14 named storms, including three to six hurricanes and one to three major hurricanes of category 3, 4, or 5 strength, packing winds of 111 mph or greater. By comparison, a typical season is characterized by 14 named storms, including seven hurricanes and three major hurricanes. The season ends November 30.

“It just takes one,” said Ken Graham, director of the National Weather Service. “Now is the time to start thinking about your hurricane preparedness.”

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Over four years after a California agency sued Tesla over an alleged pattern of racial discrimination, a judge has dismissed Tesla's motion to throw out the lawsuit.

The California Civil Rights Department (CRD) said today that the Alameda County Superior Court order clears a path for the case to go to trial, which is currently scheduled for July 20. Tesla "employment practices remain rooted in some of the ugliest relics of the past," CRD Director Kevin Kish said. "Black workers are paid less for their work. They are subjected to racist slurs. They face threats of being fired for speaking out... We look forward to having our day in court to hold Tesla accountable and to protect the rights of workers in our state.”

The lawsuit alleges widespread discrimination, especially at Tesla's Fremont factory, and seeks financial damages and injunctive relief. At trial, the case may include claims of discrimination going back to June 2018. The judge partially granted Tesla's request to block claims under the statute of limitations, but only for incidents that happened before June 18, 2018.

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Over the decades, there has been no shortage of sites using clever techniques to covertly track visitors’ browsing histories , device fingerprints , and log keystrokes and mouse movements in real time. Even Meta and Yandex were recently caught joining in the privacy-invasive free-for-all .

Now sites have a new way to spy on their visitors: measuring subtle interactions with their solid-state drives. The technique, named FROST (fingerprinting remotely using OPFS-based SSD timing), allows sites to monitor other sites a visitor is viewing and what apps are open on their devices.

A side channel based on contention

The technique, laid out in a research paper , exploits a side channel , a form of leak resulting from physical manifestations such as electromagnetic emanations, data caches, or the time required to complete a task. By measuring the manifestations, attackers can decrypt encrypted traffic and infer other confidential data.

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NASA satellites designed to observe cyclone wind speeds and collapsing ice sheets have also proven capable of identifying the approximate locations of GPS jammers. That could help monitor high-risk areas for aircraft and ships navigating the growing prevalence of GPS interference worldwide.

Two different NASA satellite systems showed how they could locate a known but mysterious GPS jammer within several kilometers of its position in Iran, according to an experiment by Sean Gorman , CEO and cofounder of the location-based technology company Zephr.xyz that was detailed in the magazine GPS World . Such jammers use strong signals to overpower the weaker radio signals coming from US-operated GPS satellites and other global navigation satellite systems.

Such NASA satellites cannot perform “near-real time monitoring” or pinpoint the exact location of GPS jammers, said Clara Chew , principal scientist and lead of the GNSS systems and data team at the California-based satellite manufacturer Muon Space, who was not involved in the study. But Chew told Ars that identifying the approximate locations of GPS jammers “could potentially be helpful for flight planning” or for “indicating high risk areas for maritime shipping.”

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Modern Legend of Zelda games like Breath of the Wild are built around Link's ability to run, climb, and jump with the best of them. In old-school, top-down Zelda titles, though, the ability to increase Link's sad starting mobility was a banner event. Finding items like the speed-enhancing Pegasus Boots in Link to the Past or the jump-granting Roc's Feather in Link's Awakening made the methodical exploration in these games feel that much more kinetic and akin to a top-down platform game.

This kind of kinetic feeling is built into Mina the Hollower from the start. As the titular, mouse-like Hollower, you're armed with the ability to jump up and burrow into soft soil, zipping under obstacles and past enemies with satisfying pep as you do. After a short sojourn underground, you pop out with an extended jump that quickly becomes second nature.

The sense of energy and verve built in to this simple movement system makes Mina a joy to control. You feel that joy when you burrow away from an enemy attack only to quickly circle back to pop out for a quick counter. You feel it burrowing underneath the scenery through a small hole to uncover a labyrinthine secret corridor. You feel it hopping and bouncing across a series of gaps on inflatable, balloon-like pads.

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In a splashy move that signals that Taiwan remains irreplaceable to the AI industry's short-term and long-term goals, Nvidia CEO Jensen Huang announced Wednesday that his chip company will invest $150 billion a year to make sure Taiwan remains at the "epicenter" of the "AI revolution."

"This is where the chips come, packaging comes, this is where the systems are made, this is where AI supercomputers were created," Huang said. "The number of partners we work with here in Taiwan, incredible."

As Reuters reported , the substantial investments will be used to create a new Taiwan headquarters for Nvidia, which Huang expects will drive so much AI innovation that the partnership will cement Taiwan as "the world's tech manufacturing hub for a long time." That ambitious project will be operational by 2030, Nvidia anticipates, after breaking ground this year.

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Roku just unveiled the biggest overhaul to its smart TV operating system (OS) in 10 years. The most noticeable difference is a new ad space that takes up a large chunk of the screen’s right side.

Before the update, loading up a Roku OS-powered smart TV or streaming device would yield a menu on the left side with sections including “What to Watch,” “Live,” and “Search.” The right side had a row of tiles for “Recommended” content above several rows of tiles representing downloaded apps.

The old Roku home screen. Credit: Roku

The right side of the new Roku OS home screen is dedicated to ads. The ad remains visible as you navigate different parts of the Roku menu, taking away space that could be used for displaying apps and content.

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Valve's Steam Deck handheld has been largely unavailable to buy since mid-February, a victim of the RAM and storage shortages that have been driving up prices for most consumer tech since the fall of 2025. The good news is that the Deck is back in stock on Valve's site and ready to ship in three to five days; the bad news is that it appears to have returned because somebody wished for it on a monkey's paw .

The 512GB version of the OLED Steam Deck now sells for a whopping $789, $240 more than its previous $549 price. The 1TB version (which also includes an anti-glare screen coating, a slightly nicer case, and an "exclusive startup movie and keyboard theme") will now run you $949, a $300 increase from its old $649 price. The old $399 base model with 256GB of storage and the older LCD screen has been discontinued, though this had been announced well before these price increases took effect.

These prices are particularly hard to swallow for a nearly 3-year-old revision of an over-4-year-old handheld PC . If there's a saving grace for Valve, it's that most competing handhelds from the likes of Asus and Lenovo are also pushing or exceeding that $1,000 mark. Of the Deck's major competitors, only the $600 Asus ROG Xbox Ally (and its AMD Ryzen Z2 A processor, which is very similar to the Deck's semi-custom AMD chip) is significantly cheaper than the Steam Deck.

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